# RD 724005
Phentolamine mesylate: new solid forms
Publication date
25/06/2024
Language
English
Paper publication
August 2024 Research Disclosure journal
Digital time stamp
e3b0c44298fc1c149afbf4c8996fb92427ae41e4649b934ca495991b7852b855
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Abstract
New Phentolamine Mesylate solid forms Abstract: The current invention discloses three new solid forms of the α-adrenergic receptor antagonist Phentolamine Mesylate Background: Phentolamine Mesylate (Phenol, 3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-, methanesulfonate, CAS 65-28-1) is a reversible, non-selective α-adrenergic antagonist primarily used in the treatment of hypertensive emergencies. The Api has the following structure formula: Figure 1: chemical structure of Phentolamine Mesylate No evidence of polymorphs, solvates,...